Rapidly attain sections as thin or thick as your software requires, without stressing about getting rid of or distorting precious tissue samples.
Megatome is often a vibrating microtome intended to area a broad number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome allows higher-throughput tissue sectioning with uniform surface profile, and nominal tissue injury and information decline.
Antibodies might choose months to diffuse via only some millimeters of tissue, using a steep labeling gradient from area to core.
Megatome is designed for precision: the blade vibrates at a higher frequency and bigger amplitude variety than other microtomes, and encompasses a special deflection Command mechanism.
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Our preformulated EasyIndex Alternative raises and homogenize the refractive index of delipidated tissue samples, rendering them totally clear. This allows light penetration to the sample and makes sure the acquisition of higher-resolution, in-emphasis graphic information.
Megatome can be a novel microtome that enables for top-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue injury and data reduction.
eFLASH is often a immediate tissue labeling technique that allows for uniform whole-organ staining in 20 rounds of labeling.
Fully delipidate whole mouse brains or comparably sized megatomi.com samples in only one working day with SmartBatch+, or in a single 7 days with our passive clearing package.
Docset development needs at minimal two choices: the name of the docset and The situation with the Javadoc documents to include within the docset.
This can make a docset named Sample in The existing Listing. Docset creation is often tailored with optional arguments:
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Leverage the Crystal clear+ tissue clearing technique, along with eFLASH and patented stochastic electrotransport systems, to rapidly apparent and label complete organs. Vital highlights and characteristics include:
Our novel Defend tissue preservation technique varieties intramolecular bonds utilizing polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.